While everyone were on the Cable or Colossus train after watching Deadpool 2 (including me) I’ve seen people argue that Wade and Dopinder probably got it on in between Deadpool and Deadpool 2, or they might in the future.
It’s already established that they’re attracted to each other. Wade keeps talking about how handsome and cute he thinks Dopinder is, and Dopinder really likes Wade’s thighs. Dopinder doesn’t just want to kill, he wants to kill Wade’s enemies, and Wade doesn’t want Dopinder to get hurt despite not being too worried about adults’ safety in general. Literally no one calls Wade by a pet name besides Vanessa and Dopinder. During the taxi ride Wade started caressing Dopinder’s face and neck, and Dopinder acted like it was perfectly normal. In fact, he’s the only man who has never complained about Wade hitting on him.
So it does seem like Vanessa gave Wade her blessing to sleep with his “boyishly handsome” getaway driver. Their last words to each other in Heaven certainly seemed to suggest that they give each other free passes and no-nos.